Propofol And Peanut Allergy. Allergies are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic dermatitis, allergic asthma, and anaphylaxis. Symptoms may include red eyes, an itchy rash, sneezing, a runny nose, shortness of breath, or swelling. Food intolerances and food poisoning are separate conditions. Read more …
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Thus, with somewhat speculative evidence, allergy to egg, peanut and soy had been causally-associated with propofol allergy. The connection It is marketed as an emulsion containing soybean oil, egg lecithin and glycerol. Several cases of allergic reactions to propofol have been published, 410 with no mention of egg, soy or peanut allergy. There are six published case reports of suspected allergy to propofol in individuals allergic to egg, soy or peanut.
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Anaesthesia. 2007 Nov;62(11):1191. Propofol and peanut allergy. Gangineni K, Scase AE, Fearn J. Comment in Anaesthesia. 2008 Apr;63(4):439. The drug, though generally considered safe, has been considered a relative contraindication in egg and soy allergic patients. Our aim was to determine whether patients with evidence of food allergy, particularly to egg, soy and/or peanut had an allergic reaction to propofol when used during their endoscopies.
The propofol is mixed in a liquid containing soybean oil and a substance called egg lecithin. Lecithin is a fatty substance found in some plant and animal tissues. Patients who are allergic to foods, including soy and egg, are allergic to proteins in the foods and are not allergic to the oils or fats in the foods. than recommended, it is my normal practice to check the length of the tube against the patient and if this is adequate to use a smaller size tube to minimise.
The potential for peanut?allergic patients to be sensitive to propofol is due to the fact that soya oil is one of the excipients of propofol, and that On Dec 1, 2007 K Gangineni (and others) published: Propofol and peanut allergy.
Moreover, in study B, no signs of allergic reactions to propofol in 171 retrieved anesthetic charts from 99 patients with specific IgE to egg, soy, or peanut were No evidence for contraindications to the use of propofol in adults allergic to egg, soy or peanut. Asserhøj et al. Br J Anaesth (2015) 116 (1):