Allergic Reaction To Aleve Hives

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Can naproxen sodium cause an allergic reaction? Naproxen sodium, the active ingre.nt in Aleve, may cause a severe allergic reaction, especially in people allergic to aspirin or other NSAIDs. Symptoms may include hives, facial swelling, asthma wheezing , shock, skin re.Important information. You should not use Aleve if you have a history of allergic reaction to aspirin or other NSAID nonsteroidal anti inflammatory drug ..